Chlorphenesin

Absorption

Rapid and complete.

Toxicity

Symptoms of a chlorphenesin overdose include drowsiness and nausea.

Chemical properties

White to Off-White Solid

The Uses of Chlorphenesin

Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. Chlorphenesin is also used as an antimycotic agent.

The Uses of Chlorphenesin

chlorophenesin is a preservative with fungistatic and bactericidal properties.

The Uses of Chlorphenesin

It is used for relieving skeletal muscle pain.

Indications

Used, along with rest and physical therapy, to treat injuries and other painful muscular conditions. Investigated for use in trigeminal neuralgia (tic douloureux), a neuropathic disorder characterized by severe facial pain. Was investigated as a modulator of histamine release.

What are the applications of Application

3-(4-Chlorophenoxy)-1,2-propanediol is an antigen-associated immunosuppressant

Definition

ChEBI: Chlorphenesin is glycerol in which the hydrogen of one of the primary hydroxy groups is substituted by a 4-chlorophenyl group. It has antifungal and antibacterial properties, and is used for treatment of cutaneous and vaginal infections. Its 1-carbamate is used as a skeletal muscle relaxant for the treatment of painful muscle spasm. It has a role as a muscle relaxant, an antibacterial drug and an antifungal drug. It is a glycol, a member of propane-1,2-diols and a member of monochlorobenzenes.

brand name

Maolate (Pharmacia & Upjohn).

Flammability and Explosibility

Not classified

Pharmacokinetics

Chlorphenesin is a muscle relaxant. It blocks nerve impulses (or pain sensations) that are sent to the brain.

Side Effects

Chlorphenesin is well tolerated with no serious adverse effects. Adverse reactions that may occur with Chlorphenesin include: drowsiness, dizziness or confusion, headache; nervousness or insomnia; or nausea or stomach upset.

Metabolism

Hepatic. 85% of a dose excreted within 24 hours as the glucuronide metabolite.