CHLOROTOXIN
- CAS NO.：163515-35-3
- Empirical Formula: C158H249N53O47S11
- Molecular Weight: 3995.70956
- MDL number: MFCD08459453
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-06-18 16:39:23
What is CHLOROTOXIN?
Description
Chlorotoxin, a relatively small (36–amino acid) peptide is what makes the venom of the deathstalker scorpion (Leiurus quinquestriatus) poisonous. In 1991, J. A. DeBin and G. R. Strichartz at Harvard Medical School discovered that its mode of toxicity is to block small-conductance chloride channels, which results in paralysis.
Chlorotoxin preferentially binds to glioma cells, which prompted researchers to investigate it as a tool for diagnosing and treating some cancers. Building upon much of this research, J. M. Olson at Fred Hutchinson Cancer Center (Seattle) discovered a way to use chlorotoxin to image cancer cells—a product he calls Tumor Paint. An unusual aspect of Olson’s work is that he funded it via crowdsourcing when he couldn’t obtain grant money through the normal channels.
The Uses of CHLOROTOXIN
Biochemical probe for voltage-gated chloride channels.
Properties of CHLOROTOXIN
| storage temp. | −20°C |
| solubility | aqueous buffer: soluble |
| form | lyophilized powder |
| color | Colorless to light yellow |
Safety information for CHLOROTOXIN
Computed Descriptors for CHLOROTOXIN
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
Chlorotoxin from Leiurus quinquestriatus (north Africa) CAS 163515-35-3View Details
163515-35-3 -
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
DL-beta-(3-Bromophenyl)alanine 117391-50-1 98+View Details
117391-50-1 -
49830-37-7 98+View Details
49830-37-7 -
3-Amino-3-(4-fluorophenyl)propanoic acid 98+View Details
325-89-3 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8