chinoin 123
- CAS NO.：64405-40-9
- Empirical Formula: C14H18N2O5
- Molecular Weight: 294.3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is chinoin 123?
Originator
Acitemate ,Onbio Inc.
Manufacturing Process
23.6 g of 3-ethoxycarbonyl-7-methyl-4-oxo-6,7,8,9-tetrahydro-4Hpyrido[
1,2a]pyrimidine and 10.0 g of glyoxylic acid monohydrate are reacted
and the obtained 3-ethoxycarbonyl-7-methyl-9-carboxy(hydroxymethyl)-4-
oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine is heated in 150 ml ethanol
under stirring for 3 h. After cooling the crystals are filtered off and
recrystallized from ethanol. Thus 3-ethoxycarbonyl-7-methyl-9-
(carboxymethylene)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine
melting point 110°-112°C, is obtained (yield: 51%).
55.6 g of 3-ethoxycarbonyl-9-(carboxymethylene)-4-oxo-6,7,8,9-tetrahydro-
4H-pyrido[1,2a]pyrimidine are hydrogenated in 500 ml of ethanol in the
presence of 20.0 g of 9% by weight Pd/C catalyst containing metal. When 1
mole of hydrogen has been used up, the catalyst is removed from the reaction
mixture by filtration and the solution is evaporated under reduced pressure.
The 3-ethoxycarbonyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9-
acetic acid is obtained (yield: 57%), melting point 156°-157°C (recrystallized
from ethanol).
Therapeutic Function
Platelet aggregation inhibitor, Antihyperlipidemic
Properties of chinoin 123
| Melting point: | 154-155 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 472.0±55.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| pka | 4.45±0.10(Predicted) |
Safety information for chinoin 123
Computed Descriptors for chinoin 123
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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