Cefbuperazone
- CAS NO.：76610-84-9
- Empirical Formula: C22H29N9O9S2
- Molecular Weight: 627.65
- MDL number: MFCD00864869
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-18 11:52:23
What is Cefbuperazone?
The Uses of Cefbuperazone
Cefbuperazone is a second-generation cephalosporin antibiotic.
Definition
ChEBI: Cefbuperazone is a second-generation cephamycin antibiotic having [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and {N-[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]-D-threonyl}amino side groups located at positions 3 and 7beta respectively. It is a peptide and a cephalosporin.
Antimicrobial activity
Cefbuperazone is a semisynthetic cephamycin antibiotic with properties similar to those of cefoxitin, but somewhat more active against B. fragilis and enterobacteria. It is not hydrolyzed by common β-lactamases and as a result its activity is not affected by inoculum size. It is not active against cefoxitin-resistant strains. It is available in Japan.
Properties of Cefbuperazone
| Melting point: | 118-120° (dec) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for Cefbuperazone
Computed Descriptors for Cefbuperazone
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