Cefaclor monohydrate

CAS NO.：70356-03-5
Empirical Formula: C15H16ClN3O5S
Molecular Weight: 385.82
MDL number: MFCD00071999
EINECS: 641-991-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-19 07:28:27

What is Cefaclor monohydrate?

Description

Cefaclor was found by Eli Lilly & Co. in 1976 in the course of studies on the improvement of synthetic procedures for cephalexin. The intermediates with chlorine at the 3 position of the cephem nucleus have excellent antibacterial activity. Cefaclor was selected from among the various derivatives that differed at the 7 position because of its strong activity and high bioavailability following oral administration.

Chemical properties

Crystalline Solid

The Uses of Cefaclor monohydrate

Second-generation cephalosporin antibiotic. Antibacterial

The Uses of Cefaclor monohydrate

Antibacterial;Bacterial transpeptidase inhibitor

The Uses of Cefaclor monohydrate

Second-generation cephalosporin antibiotic. Antibacterial.

What are the applications of Application

Cefaclor, Monohydrate is a potentially useful antimicrobial agent for in vitro studies of pathogens

brand name

Ceclor (Lilly); Raniclor (Ranbaxy).

Contact allergens

Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions.

Properties of Cefaclor monohydrate

Melting point:	>180°C (dec.)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Slightly soluble in water, practically insoluble in methanol and in methylene chloride.
form	neat
form	Solid
color	White to Light Beige
CAS DataBase Reference	70356-03-5(CAS DataBase Reference)

Safety information for Cefaclor monohydrate

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.