Cytidine 5'-diphosphate trisodium salt

Chemical properties

White crystalline powder

The Uses of Cytidine 5'-diphosphate trisodium salt

Cytidine 5′-diphosphate sodium salt hydrate has been used:

• as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections
• in ribonucleotide reductase assay
• dCDP formation assay.

The Uses of Cytidine 5'-diphosphate trisodium salt

Cytidine 5'-Diphosphate trisodium salt is a diphosphate nucleoside derived from Cytidine (C998300). An inhibitor of glycogenin-catalyzed glucosyl and xylosyl transfer It is used as a therapeutic agent in treatment prevention of myocardial isc hemia accompanied with cerebral ischemia.

General Description

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.

Biochem/physiol Actions

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.