Cathine hydrochloride

Synonym(s):(+)-Cathine;(+)-Pseudonorephedrine;(1S,2S)-2-Amino-1-phenyl-1-propanol;D-(+)-Norpseudoephedrine

CAS NO.：492-39-7
Empirical Formula: C9H13NO
Molecular Weight: 151.21
MDL number: MFCD00070245
EINECS: 207-754-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:52:16

What is Cathine hydrochloride?

The Uses of Cathine hydrochloride

An enantiomer of phenylpropanolamine and a metabolite of cathinone.

Definition

ChEBI: Cathine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer). It has a role as a plant metabolite, a central nervous system stimulant and a psychotropic drug. It is a member of amphetamines and a phenethylamine alkaloid.

brand name

Adiposetten n;Amorphan depot;Andiposetten;Appetrol;Dietene;Exponcit;Insacial;Miniscap;Minusin depot;Mirapront n;Neo-soldana;Novese;Phyteia schlankheitsdragees;Reduform;Redufrom;Thinz.

World Health Organization (WHO)

Cathine, a sympathomimetic amine, was formerly widely available in proprietary anorexic preparations. As dependence can occur and abuse has been reported, cathine has recently (1986) been subjected to control under Schedule III of the 1971 Convention on Psychotropic Substances. (Reference: (UNCPS3) United Nations Convention on Psychotropic Substances (III), , , 1971)

Safety Profile

Poison by subcutaneous route.When heated to decomposition it emits toxic vapors ofNOx.

Properties of Cathine hydrochloride

Melting point:	77.5-78°
Boiling point:	273.23°C (rough estimate)
alpha	20546 +37.9° (c = 3 in methanol)
Density	1.0406 (rough estimate)
refractive index	1.5380 (estimate)
storage temp.	2-8°C
solubility	H₂O: ~20 mg/mL
form	solid
pka	8.92(at 25℃)
color	white
optical activity	[α]/D +34.0±2.0°, c = 3.5 in ethanol
EPA Substance Registry System	Benzenemethanol, .alpha.-[(1S)-1-aminoethyl]-, (.alpha.S)- (492-39-7)

Safety information for Cathine hydrochloride

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.