Carboxyatractyloside
- CAS NO.：77228-71-8
- Empirical Formula: C31H46O18S2
- Molecular Weight: 770.81
- MDL number: MFCD00152201
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-05 13:14:27
What is Carboxyatractyloside?
The Uses of Carboxyatractyloside
Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.
Biochem/physiol Actions
Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.
Properties of Carboxyatractyloside
| Density | 1.58±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: ≥10mg/mL |
| pka | -3?+-.0.18(Predicted) |
| form | solid |
| color | white |
Safety information for Carboxyatractyloside
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Carboxyatractyloside
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
![dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate](https://img.chemicalbook.in/CAS/GIF/33286-30-5.gif)
You may like
-
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.