BZ-NLE-LYS-ARG-ARG-AMC

CAS NO.：863975-32-0
Empirical Formula: C41H60N12O7
Molecular Weight: 832.99
MDL number: MFCD18782523
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-21 10:31:43

What is BZ-NLE-LYS-ARG-ARG-AMC?

Description

Bz-Nle-KRR-AMC is a fluorogenic peptide substrate for yellow fever virus (YFV) non-structural 3 (NS3) and dengue virus (DV) NS2B/3 serine proteases. Upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify YFV NS3 or DV NS2B/3 serine protease activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

Properties of BZ-NLE-LYS-ARG-ARG-AMC

storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form	A solid

Safety information for BZ-NLE-LYS-ARG-ARG-AMC

Computed Descriptors for BZ-NLE-LYS-ARG-ARG-AMC

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