BUTEIN
Synonym(s):1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one;2′,3,4,4′-Tetrahydroxychalcone
- CAS NO.：21849-70-7
- Empirical Formula: C15H12O5
- Molecular Weight: 272.25
- MDL number: MFCD00017300
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is BUTEIN?
The Uses of BUTEIN
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent.
Definition
ChEBI: Butein is a chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. It has a role as a tyrosine kinase inhibitor, an antioxidant, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an antineoplastic agent, a geroprotector, a radiosensitizing agent, a hypoglycemic agent and a plant metabolite. It is a member of chalcones and a polyphenol.
Properties of BUTEIN
| Melting point: | 250-252℃ |
| Boiling point: | 560.9±50.0 °C(Predicted) |
| Density | 1.483±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO: >50 mg/mL |
| form | solid |
| pka | 7.34±0.35(Predicted) |
| color | yellow |
Safety information for BUTEIN
Computed Descriptors for BUTEIN
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