Butanedihydrazide

CAS NO.：4146-43-4
Empirical Formula: C4H10N4O2
Molecular Weight: 146.15
MDL number: MFCD00007613
EINECS: 223-970-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:18:58

What is Butanedihydrazide?

The Uses of Butanedihydrazide

Succinic dihydrazide (SDH) is an important organic compound used as aqueous coating auxiliary, epoxy cross-linking agent, deoxidiser, textile auxiliary, and biochemical reagent, mainly in laboratory organic synthesis processes and in research and development in chemical and pharmaceutical manufacturing. SDH has been shown to be a nitrogen atom donor for the preparation of nitride [M(N)]-complexes (M = 99mTc and 188Re)^[1].

References

[1] DAVIDE CARTA . Assessment of the best N3 ? donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)[J]. Nuclear medicine and biology, 2014. DOI:10.1016/j.nucmedbio.2014.04.126.

Properties of Butanedihydrazide

Melting point:	170-171 °C (lit.)
Boiling point:	540.2±33.0 °C(Predicted)
Density	1.284±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Water Solubility	Soluble in water
form	powder to crystal
pka	12.62±0.35(Predicted)
color	White to Almost white
CAS DataBase Reference	4146-43-4(CAS DataBase Reference)
NIST Chemistry Reference	Butanedioyl dihydrazide(4146-43-4)

Safety information for Butanedihydrazide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.