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BTA-1

BTA-1 Structural

What is BTA-1?

Biochem/physiol Actions

BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier.

Properties of BTA-1

Boiling point: 415.5±47.0 °C(Predicted)
Density  1.258±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: soluble ~10mg/mL
pka 2.58±0.12(Predicted)
form  solid
color  yellow

Safety information for BTA-1

Computed Descriptors for BTA-1

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