BRUSATOL
Synonym(s):(+)-Brusatol;(11β,12α,15β)-13,20-Epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-picras-3-en-21-oic acid methyl ester;Brutasol;NSC 172924;Yatansin
- CAS NO.：114420-67-6
- Empirical Formula: C20H26O11
- Molecular Weight: 442.41
- MDL number: MFCD32263358
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is BRUSATOL?
The Uses of BRUSATOL
Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.
Properties of BRUSATOL
| Boiling point: | 727.5±60.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| form | Solid |
| pka | 8.58±0.15(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 114420-67-6 |
Safety information for BRUSATOL
Computed Descriptors for BRUSATOL
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