Borane-2-picoline complex

Synonym(s):2-Picoline borane complex;2-Picoline borane complex solution

CAS NO.：3999-38-0
Empirical Formula: C6H10BN
Molecular Weight: 106.96
MDL number: MFCD07784361
EINECS: 609-767-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:19:52

What is Borane-2-picoline complex?

The Uses of Borane-2-picoline complex

Environmentally benign reducing agent. Reactant for: Reductive amination. N-Benzyl-protection of amino acid derivatives by reductive alkylation. Reductive alkoxyamination.

The Uses of Borane-2-picoline complex

Used as reactant for N-Benzyl-protection of amino acid derivatives by reductive alkylation, reductive alkoxyamination, as reducing agent for the labeling of oligosaccharides by reductive amination, synthesis of alkoxyamine derivatives, via reduction of oxime ethers, reductive amination reactions of C1-C10 aldehyde 2,4-dinitrophenylhydrazones, synthesis of various trifluoromethylated amino compounds and an alternative reagent for reductive aminations.

What are the applications of Application

2-Picoline borane complex is a reagent for reductive aminations

General Description

2-Methylpyridine borane complex is a nontoxic alternate to the reducing agent sodium cyanoborohydride.

Properties of Borane-2-picoline complex

Melting point:	48 °C
Density	1.297 g/mL at 25 °C
Flash point:	100°(212°F)
storage temp.	2-8°C
solubility	Dichloromethane (Sparingly), Ethyl Acetate (Slightly)
form	Solid
color	White
Water Solubility	Slightly sol. in water, cyclohexane, very sol. in methanol, THF, diglyme, and benzene
Sensitive	Moisture Sensitive

Safety information for Borane-2-picoline complex

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H261:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P231+P232:Handle under inert gas. Protect from moisture. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.