Boldine dimethyl ether
- CAS NO.:475-81-0
- Empirical Formula: C21H25NO4
- Molecular Weight: 355.43
- MDL number: MFCD00075953
- EINECS: 207-501-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:56:34
What is Boldine dimethyl ether?
Description
Glaucine (Item No. 17338) is an analytical reference standard categorized as an antitussive. Glaucine has hallucinogenic properties. This product is intended for research and forensic applications.
The Uses of Boldine dimethyl ether
d-Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries.
Definition
ChEBI: (S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups. It has a role as a platelet aggregation inhibitor, a NF-kappaB inhibitor, an antitussive, an antibacterial agent, a muscle relaxant, an antineoplastic agent, a plant metabolite and a rat metabolite. It is an aporphine alkaloid, a polyether, an organic heterotetracyclic compound and a tertiary amino compound. It is a conjugate base of a (S)-glaucine(1+).
Properties of Boldine dimethyl ether
| Melting point: | 246-247℃ |
| Boiling point: | 488.45°C (rough estimate) |
| alpha | D20 +115° (c = 3 in alc) |
| Density | 1.166±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5614 (estimate) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.35±0.20(Predicted) |
| color | Pale Beige |
Safety information for Boldine dimethyl ether
Computed Descriptors for Boldine dimethyl ether
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