Boc-Hyp-OH
Synonym(s):trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L -proline;Boc-L -hydroxyproline
- CAS NO.：13726-69-7
- Empirical Formula: C10H17NO5
- Molecular Weight: 231.25
- MDL number: MFCD00053370
- EINECS: 604-011-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 16:04:00
What is Boc-Hyp-OH?
Chemical properties
White powder
The Uses of Boc-Hyp-OH
Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
Biological Activity
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Properties of Boc-Hyp-OH
| Melting point: | 123-127 °C(lit.) |
| Boiling point: | 390.9±42.0 °C(Predicted) |
| alpha | -78 º (in H2O) |
| Density | 1.312±0.06 g/cm3(Predicted) |
| refractive index | -68 ° (C=1, MeOH) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 3.80±0.40(Predicted) |
| color | White to off-white |
| optical activity | [α]20/D 53.5±2°, c = 1% in DMF |
| Water Solubility | very faint turbidity |
| BRN | 4295484 |
| CAS DataBase Reference | 13726-69-7(CAS DataBase Reference) |
| EPA Substance Registry System | (2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7) |
Safety information for Boc-Hyp-OH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Boc-Hyp-OH
| InChIKey | BENKAPCDIOILGV-RQJHMYQMSA-N |
Boc-Hyp-OH manufacturer
BTC pharm India
4Y
Phone:+91-8790379245
Whatsapp: +91- 6361382515
product: 13726-69-7 Boc-Hyp-OH 98+
New Products
(E)-1-Ethoxyethene-2-boronic Acid Pinacol Ester 1,3-Diethyl-1,3-Diphenylurea 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,4-dihydroxybenzaldehyde 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 1,3-Di Iodo Benzene Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 3-Hydroxy-4-nitrobromobenzene 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoate Thio AcetamideRelated products of tetrahydrofuran
![(2S,4R)-1-(tert-butoxycarbonyl)-4-[2-fluoro-3-(trifluoromethyl)phenoxy]pyrrolidine-2-carboxylic acid](https://img.chemicalbook.in/StructureFile/ChemBookStructure23/GIF/CB41078378.gif)
You may like
-
13726-69-7 98%View Details
13726-69-7 -
13726-69-7 (2S,4R)-1-(tert-butoxycarbonyl)-4- hydroxypyrrolidine-2-carboxylic acid; N-tert-butoxycarbonyl-L-trans-4- hydroxyproline 98%View Details
13726-69-7 -
N-Boc-(2S,4R)-4-hydroxyproline 98% CAS 13726-69-7View Details
13726-69-7 -
trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline CAS 13726-69-7View Details
13726-69-7 -
Boc-Hyp-OH (cryst) CAS 13726-69-7View Details
13726-69-7 -
Boc-Hyp-OH CAS 13726-69-7View Details
13726-69-7 -
13726-69-7 Boc-Hyp-OH 98+View Details
13726-69-7 -
13726-69-7 BOC-L-4-HYDROXYPROLINE 98+View Details
13726-69-7
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.