BMS-1001
- CAS NO.：2113650-03-4
- Empirical Formula: C35H34N2O7
- Molecular Weight: 594.65
- MDL number: MFCD32709962
- Update Date: 2026-06-03 11:24:09
What is BMS-1001?
The Uses of BMS-1001
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction (IC50: 2.25 nM in a homogeneous time-resolved fluorescence binding assay).
Biological Activity
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. It attenuates the inhibitory effect of soluble PD-L1 on T cell receptor-mediated T lymphocyte activation.
Properties of BMS-1001
| Boiling point: | 801.2±65.0 °C(Predicted) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 50 mg/mL (84.08 mM);Ethanol: Insoluble |
| pka | 2.08±0.10(Predicted) |
| Water Solubility | Water: Insoluble |
Safety information for BMS-1001
Computed Descriptors for BMS-1001
New Products
Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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