BISNORCHOLENALDEHYDE

CAS NO.：3986-89-8
Empirical Formula: C22H32O2
Molecular Weight: 328.49
MDL number: MFCD00056488
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 04:11:30

What is BISNORCHOLENALDEHYDE?

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

The Uses of BISNORCHOLENALDEHYDE

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

Properties of BISNORCHOLENALDEHYDE

Melting point:	159-160 °C
Boiling point:	459.4±14.0 °C(Predicted)
Density	1.07±0.1 g/cm3(Predicted)
solubility	Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White