Bis(NHS)PEG5
Synonym(s):Bis-N-succinimidyl-(pentaethylene glycol) ester;Bis-succinimide ester-activated PEG compound
- CAS NO.：756526-03-1
- Empirical Formula: C22H32N2O13
- Molecular Weight: 532.5
- MDL number: MFCD11041118
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is Bis(NHS)PEG5?
Description
Bis-PEG5-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
The Uses of Bis(NHS)PEG5
Bis(NHS)PEG5 is used in targeting M2-like tumor-associated macrophages by using melittin-based pro-apoptotic peptide conjugates with anti-cancer drugs,
General Description
By contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications. Homobifunctional crosslinkers containing N-hydroxysuccinimide (NHS) esters are often used for low-resolution 3-D studies of protein structure and protein interaction analysis.
Properties of Bis(NHS)PEG5
| Boiling point: | 632.5±65.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO, DCM, DMF |
| form | solid or viscous liquid |
| color | Colorless to Almost colorless |
| CAS DataBase Reference | 756526-03-1 |
Safety information for Bis(NHS)PEG5
Computed Descriptors for Bis(NHS)PEG5
New Products
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