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HomeProduct name listBetulin-3-acetate

Betulin-3-acetate

Betulin-3-acetate Structural

What is Betulin-3-acetate?

Biological Activity

3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.

References

1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)

Properties of Betulin-3-acetate

storage temp.  -20°C
solubility  DMF: 5 mg/ml
form  A crystalline solid

Safety information for Betulin-3-acetate

Computed Descriptors for Betulin-3-acetate

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