BAY 299
- CAS NO.：2080306-23-4
- Empirical Formula: C25H23N3O4
- Molecular Weight: 429.47
- MDL number: MFCD30480933
- Update Date: 2025-12-04 14:24:59
What is BAY 299?
Description
BAY-299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 (IC50 = 6 nM), also known as BRPF2, and the second bromodomain of transcription initiation factor TFIID subunits 1 (TAF1; IC50 = 13 nM). BAY-299 is >30-fold selective over BRPF1, BRPF3, BRD9, and ATAD2 and is >300-fold selective over BRD4. See the Structural Genomics Consortium (SGC) website for more information.
The Uses of BAY 299
BAY 299, is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1, also known as BRPF2, and a strong inhibitor of TAF1/TAF1L BD2. These proteins play important roles in transcription regulation.
Storage
Store at -20°C
Properties of BAY 299
| Boiling point: | 688.7±55.0 °C(Predicted) |
| Density | 1.377±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:30.0(Max Conc. mg/mL);69.85(Max Conc. mM) DMF:30.0(Max Conc. mg/mL);69.85(Max Conc. mM) |
| form | A crystalline solid |
| pka | 14.98±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for BAY 299
Computed Descriptors for BAY 299
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