Baricitinib

CAS NO.：1187594-09-7
Empirical Formula: C16H17N7O2S
Molecular Weight: 371.42
MDL number: MFCD21608464
SAFETY DATA SHEET (SDS)
Update Date: 2025-10-14 17:28:45

What is Baricitinib?

Definition

ChEBI: Baricitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis. It has a role as an antirheumatic drug, an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, an anti-inflammatory agent, an immunosuppressive agent and an antiviral agent. It is a pyrrolopyrimidine, a member of pyrazoles, a member of azetidines, a sulfonamide and a nitrile.

Properties of Baricitinib

Density	1.56±0.1 g/cm3(Predicted)
pka	11.66±0.50(Predicted)

Safety information for Baricitinib

Computed Descriptors for Baricitinib

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