Azithromycin dihydrate
Synonym(s):N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;CP-62993
- CAS NO.:117772-70-0
- Empirical Formula: C38H74N2O13
- Molecular Weight: 767.01
- MDL number: MFCD01862248
- EINECS: 641-134-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Azithromycin dihydrate?
Chemical properties
White Solid
The Uses of Azithromycin dihydrate
Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis. It shows an azalide antimicrobial agent active in vitro against various pathogens.
The Uses of Azithromycin dihydrate
Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
The Uses of Azithromycin dihydrate
H1 antihistamine, nonsedating
Definition
ChEBI: Azithromycin dihydrate is a hydrate. It contains an azithromycin.
brand name
Zithromax (Pfizer); Zmax (Pfizer).
Biochem/physiol Actions
Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.
Azithromycin dihydrate application
Azithromycin Dihydrate is an azalide antimicrobial agent active in vitro against various pathogens.
Indications
Azithromycin dihydrate is a broad-spectrum macrolide antibiotic, it is effective against various gram-negative and gram-positive bacteria. It has also displayed efficacy against certain Mycoplasma species. It also exhibits anti-inflammatory and immunosuppressive properties.
Side Effects
Most common adverse reactions of azithromycin dihydrate are diarrhea (5 to 14%), nausea (3 to 18%), abdominal pain (3 to 7%), or vomiting (2 to 7%).
Properties of Azithromycin dihydrate
| Melting point: | 126 C |
| Boiling point: | 717℃ |
| alpha | D26 -41.4° (c = 1 in CHCl3) |
| refractive index | -47 ° (C=2, EtOH) |
| RTECS | RN6960000 |
| Flash point: | >110°(230°F) |
| storage temp. | room temp |
| solubility | Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride |
| form | powder |
| color | off-white |
| Sensitive | Air Sensitive |
| Merck | 14,915 |
| EPA Substance Registry System | 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-, dihydrate, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- (117772-70-0) |
Safety information for Azithromycin dihydrate
| Signal word | Danger |
| Pictogram(s) |
![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Azithromycin dihydrate
Azithromycin dihydrate manufacturer
Omicron Pharmatech Private Limited
Kromozome
Attar Global
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