AZD2624

CAS NO.：941690-55-7
Empirical Formula: C26H25N3O3S
Molecular Weight: 459.56
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-22 18:57:36

What is AZD2624?

The Uses of AZD2624

MLE-4901, is a neurokinin-3 receptor (NK3R) antagonist.

Definition

ChEBI: Pavinetant is a member of the class of quinolines that is the amide obtained by formal condensation of the carboxy group of 3-[(methanesulfonyl)amino]-2-phenylquinoline-4-carboxylic acid with the amino group of (1S)-1-phenylpropan-1-amine. A neurokinin-3 receptor antagonist that has been trialled as a potential drug for treatment of schizophrenia and menopausal symptoms. It has a role as a neurokinin-3 receptor antagonist and an antipsychotic agent. It is a member of quinolines, a secondary carboxamide, a sulfonamide and an aromatic amide.

Properties of AZD2624

Density	1.285±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:3): 0.25mg/mL; DMSO: 20mg/mL
form	A crystalline solid
pka	1.35±0.30(Predicted)
color	White to off-white

Safety information for AZD2624

Computed Descriptors for AZD2624

New Products

Dexamethasone Sodium Phosphate 2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 2-Fluoro-6-iodobenzoic acid 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate 1-Boc-4-cyanopiperidine 3-Pyridineacrylic acid Abiraterone Ethyl Ether Vardenafil Bis-sulphonamide(Dimer) 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5