Axitinib Impurity a
- CAS NO.：1347304-18-0
- Empirical Formula: C22H18N4O2S
- Molecular Weight: 402.47
- MDL number: MFCD30747237
- Update Date: 2025-08-20 16:56:12
What is Axitinib Impurity a?
Description
Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.
The Uses of Axitinib Impurity a
Axitinib Sulfoxide is a major metabolite of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Properties of Axitinib Impurity a
| Melting point: | >225 (dec.) |
| Boiling point: | 720.6±60.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 11.70±0.40(Predicted) |
| color | Light Yellow |
Safety information for Axitinib Impurity a
Computed Descriptors for Axitinib Impurity a
New Products
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