Axitinib Impurity a
- CAS NO.：1347304-18-0
- Empirical Formula: C22H18N4O2S
- Molecular Weight: 402.47
- MDL number: MFCD30747237
- Update Date: 2025-08-20 16:56:12
What is Axitinib Impurity a?
Description
Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.
The Uses of Axitinib Impurity a
Axitinib Sulfoxide is a major metabolite of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Properties of Axitinib Impurity a
| Melting point: | >225 (dec.) |
| Boiling point: | 720.6±60.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 11.70±0.40(Predicted) |
| color | Light Yellow |
Safety information for Axitinib Impurity a
Computed Descriptors for Axitinib Impurity a
New Products
Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4,4-Diethoxybutanenitrile 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Aminobenzo[d]thiazol-4-ol 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acid N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide 2-(difluoromethyl)-4H-chromen-4-oneRelated products of tetrahydrofuran
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