ATL-802

CAS NO.：847612-12-8
Empirical Formula: C24H22F3N7O3
Molecular Weight: 513.47
Update Date: 2026-04-20 17:00:22

What is ATL-802?

Description

ATL802 is an adenosine A2B Receptor antagonist. After IR, ATL802 treatment significantly improved lung function (increased pulmonary compliance and reduced airway resistance and pulmonary artery pressure) and significantly attenuated proinflammatory cytokine production, neutrophil infiltration, vascular permeability, and edema. ATL802 also significantly improved the function of DCD lungs after EVLP (increased compliance and reduced pulmonary artery pressure). After HR, A549 cells exhibited robust production of interleukin (IL)-8, a potent neutrophil chemokine, which was significantly attenuated by ATL802.

Properties of ATL-802

Boiling point:	738.0±70.0 °C(Predicted)
Density	1.481±0.06 g/cm3(Predicted)
pka	10.62±0.20(Predicted)

Safety information for ATL-802

Computed Descriptors for ATL-802

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