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HomeProduct name listARQ-531

ARQ-531

  • CAS NO.:2095393-15-8
  • Empirical Formula: C25 H23 Cl N4 O4
  • Molecular Weight: 0
  • MDL number: MFCD31692379
  • Update Date: 2025-07-04 15:21:00
ARQ-531 Structural

What is ARQ-531?

The Uses of ARQ-531

ARQ 531 is a reversible non-covalent inhibitor of Bruton’s Tyrosine Kinase (BTK),with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It shows strong target inhibition in TMD8 cell line.

Properties of ARQ-531

storage temp.  Store at -20°C
solubility  DMSO : ≥ 50 mg/mL (104.40 mM)
form  Solid
color  White to off-white

Safety information for ARQ-531

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for ARQ-531

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