APOFERRITIN
Synonym(s):Ferritin, Apo-, Equine Spleen
- CAS NO.：9013-31-4
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00081365
- Update Date: 2026-01-13 11:10:31
What is APOFERRITIN?
The Uses of APOFERRITIN
Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin. Apoferritin is used as a novel nanocarrier to load methylene blue (MB) and demonstrate its potential applications for photodynamic therapy of cancer.
The Uses of APOFERRITIN
Apoferritin from equine spleen has been used:
- to determine its partition coefficients in phase systems
- in NaCl for iron loading of cultured cells
- in in situ liquid scanning transmission electron microscope for imaging the interface of biology and nanotechnology
The Uses of APOFERRITIN
Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin IX.
Biochem/physiol Actions
This protein shell of ferritin lacking iron is widely used for the calibration of gel filtration columns and sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis. It is very abundant in beta-cells of the pancreas where it acts as an anti-oxidant. When added to cultured endothelial cells apoferritin is taken up in a dose-responsive manner and appears to protect the cells from oxidant-mediated cytolysis.
Properties of APOFERRITIN
| storage temp. | -20°C |
| solubility | Reconstitute in 0.15M NaCl |
| form | White lyophilized solid |
| color | clear to slightly hazy, solution |
Safety information for APOFERRITIN
Computed Descriptors for APOFERRITIN
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