Anti-Troponin T antibody, Mouse monoclonal
Synonym(s):Anti-TNNT1;Anti-TNNT2
- Molecular Weight: 0
- Update Date: 2025-01-27 09:38:02
What is Anti-Troponin T antibody, Mouse monoclonal?
The Uses of Anti-Troponin T antibody, Mouse monoclonal
- Anti-Troponin T antibody, Mouse monoclonal has been used in:
- immunoblotting
- immunofluorescence
- immunohistochemistry
General Description
Anti-Troponin T antibody, Mouse monoclonal, (mouse IgG1 isotype) is derived from the JLT-12 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with purified Troponin T from rabbit skeletal muscle. Troponin T (TNNT) is the tropomyosin binding subunit of the troponin complex. Three genes have evolved to encode the cardiac (TNNT2), slow (TNNT1) and fast (TNNT3) skeletal muscle Troponin T proteins, which are specifically expressed in cardial, slow and fast skeletal muscles, respectively.
Biochem/physiol Actions
Troponin T (TNNT) participates in calcium regulation of actin thin filament function and is required for the contraction of striated muscles. Levels of cardiac Troponin T serve as a sensitive biomarker of myocardial injury. Troponin T has also been suggested as a potential marker in diagnosis of skeletal myopathies including amyotrophic lateral sclerosis (ALS).
Properties of Anti-Troponin T antibody, Mouse monoclonal
| storage temp. | -20°C |
| form | buffered aqueous solution |
Safety information for Anti-Troponin T antibody, Mouse monoclonal
Computed Descriptors for Anti-Troponin T antibody, Mouse monoclonal
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