Anti-transmembrane protein 119
Synonym(s):Anti-transmembrane protein 119
- Molecular Weight: 0
- Update Date: 2025-01-27 09:38:02
What is Anti-transmembrane protein 119?
The Uses of Anti-transmembrane protein 119
Anti-TMEM119 antibody produced in rabbit has been used in immunohistochemistry.
General Description
Transmembrane protein 119 (TMEM119) is encoded by the gene mapped to human chromosome 12q23.3. The encoded protein belongs to the transmembrane protein family. TMEM119 has an O-glycosylated N-terminal region.
Biochem/physiol Actions
Transmembrane protein 119 (TMEM119) acts as an osteoinductive factor and facilitates proliferation, migration and invasion of osteosarcoma cells.(28} It is a critical molecule acting downstream of the parathyroid hormone (PTH) and similar to mothers against decapentaplegic-3 (Smad3) signaling pathways in osteoblasts. TMEM119 is considered to be a potential microglial marker that differentiates resident microglia from blood-derived macrophages in the human brain. Mutation in the gene is associated with the development of osteosarcoma.
Properties of Anti-transmembrane protein 119
| storage temp. | -20°C |
| form | buffered aqueous glycerol solution |
Safety information for Anti-transmembrane protein 119
Computed Descriptors for Anti-transmembrane protein 119
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