Anti-SDOS

The Uses of Anti-SDOS

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

General Description

Nudix hydrolase 16 like 1 (NUDT16L1) also known as TIRR (tudor interacting repair regulator), specifically interacts with the ionizing radiation induced foci formation (IRIF) region of P53 binding protein 1 (53BP1). The gene is located on human chromosome 16p13.3. The protein is a member of nucleoside diphosphate-linked moiety X (Nudix) hydrolases family.

Biochem/physiol Actions

Nudix hydrolase 16 like 1 (NUDT16L1) acts as an inhibitor of P53 binding protein 1 (53BP1). The protein repairs double strand breaks by masking the histone methyl-lysine binding function of P53 binding protein 1 (53BP1).