Anti-Nuclear protein, transcriptional regulator, 1

Synonym(s):Anti-COM1;Anti-Nuclear protein, transcriptional regulator, 1

Molecular Weight: 0
Update Date: 2026-01-13 11:21:58

What is Anti-Nuclear protein, transcriptional regulator, 1?

The Uses of Anti-Nuclear protein, transcriptional regulator, 1

Anti-NUPR1 (47-60) antibody produced in rabbit has been used in western blot analysis.

General Description

The NUPR1 (nuclear protein 1, transcriptional regulator) gene is mapped to human chromosome 16p11.2 and encodes a chromatin remodeling protein of 8.8?KDa.

Biochem/physiol Actions

Nupr1 (nuclear protein 1, transcriptional regulator) is a stress response factor, induced by lipopolysaccharides, CCl4, starvation, cell cycle arrest and other protein stimuli. NUPR1 is associated with tumor cell proliferation, metastasis and apoptosis, also regulates entosis, matrix remodeling and autophagy. It serves as a substrate for protein kinase A. Overexpression of this gene is observed in glioblastoma and hepatocellular carcinoma. The protein function is tissue specific and differs at molecular level. It can act as a tumor suppressor or inducer.

Properties of Anti-Nuclear protein, transcriptional regulator, 1

storage temp.	-20°C
form	buffered aqueous solution

Safety information for Anti-Nuclear protein, transcriptional regulator, 1

Computed Descriptors for Anti-Nuclear protein, transcriptional regulator, 1

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