Anti-NF-EM5 antibody produced in rabbit

The Uses of Anti-NF-EM5 antibody produced in rabbit

Rabbit Anti-IRF4 antibody can be used for western blot applications at a concentration of 5μg/ml.

General Description

IRF4 is a transcription factor that is expressed primarily in the lymphocytes. Studies in mice have shown that IRF4 deficiencies can cause lymphadenopathy. IRF4 defects can also lead to impaired cytotoxic and anti-cancer responses.
Rabbit Anti-IRF4 antibody recognizes bovine, pig, zebrafish, chicken, canine, human, mouse, and rat IRF4.

Biochem/physiol Actions

IFN regulatory factor (IRF)-4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin).