Anti-MRTF-A

Synonym(s):Anti-Adapter protein wyatt;Anti-BSAC;Anti-MAL;Anti-megakaryoblastic leukemia (translocation) 1;Anti-MRTF-A

Molecular Weight: 0
MDL number: MFCD03456039
Update Date: 2025-01-27 09:38:02

What is Anti-MRTF-A?

The Uses of Anti-MRTF-A

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

General Description

The gene MKL1 (megakaryoblastic leukemia (translocation) 1) is mapped to human chromosome 22q13.2. It belongs to the myocardin-related family of transcriptional coactivators. The protein is present in the cytoplasm and nucleus. It is widely expressed in human tissues.

Biochem/physiol Actions

MKL1 (megakaryoblastic leukemia (translocation) 1) is a transcriptional coactivator. G-actin interacts with MKL1 and prevents its association with transcription factor SRF (serum response factor). Release of MKL1 from G-actin results in an interaction between SRF and MKL1. This association controls the expression of cytoskeletal proteins. MKL1 is also involved in skeletal, cardiac and smooth muscle differentiation. It also enhances tumor cell invasion and metastasis.

Properties of Anti-MRTF-A

storage temp.	-20°C
form	buffered aqueous glycerol solution

Safety information for Anti-MRTF-A

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Anti-MRTF-A

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