ANTI-MINT1

Synonym(s):Anti-Amyloid β (A4) precursor protein-binding, family A, member 1 (X11);Anti-Amyloid-β;Anti-MINT1;Anti-X11;Anti-X11A

Molecular Weight: 0
MDL number: MFCD02263654
Update Date: 2026-01-13 11:23:24

What is ANTI-MINT1?

The Uses of ANTI-MINT1

Anti- APBA1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.

General Description

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) is a neuronal adaptor protein belonging to the X11 family. It consists of a centrally located phosphotyrosine binding domain, which inhibits the production of Aβ peptide, two C-terminal postsynaptic density-95, large discs, zona occludens 1 (PDZ) domains.

Biochem/physiol Actions

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) stabilizes amyloid precursor protein (APP) by directly interacting with it. It also restricts production as well as accumulation of proteolytic APP fragment in the brain of Alzheimer′s disease patients. It also suppresses glycogen synthase kinase-3β promoter activity by coupling with a silencer binding protein.

Properties of ANTI-MINT1

storage temp.	−20°C
form	buffered aqueous solution

Safety information for ANTI-MINT1

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for ANTI-MINT1

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