ANTI-HUMAN IGG (FC)

The Uses of ANTI-HUMAN IGG (FC)

Anti-Human IgG (Fc specific) antibody produced in goat has been used:

• in double-capture ELISA to measure antiglobulin responses in serum of transplant patients treated with CD52 monoclonal antibodies (CAMPATH-1G)
• in detection of IgG levels rheumatoid arthritis patients
• in small intestine biopsies
• in patients with acute myocardial infarction by immunoblotting

The Uses of ANTI-HUMAN IGG (FC)

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse has been used in:

• enzyme linked immunosorbent assay (ELISA)
• imprint immunofixation (IIF)
• immunofluorometric assay (IFMA)
• hemagglutination (HA)
• hemagglutination inhibition (HAI)
• particle counting immunoassay(PACIA)

The Uses of ANTI-HUMAN IGG (FC)

Anti-Human IgG (Fc specific) antibody produced in rabbit has been used as a control in cysteine-rich angiogenic inducer 61 (CYR61) blocking experiment.

General Description

Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

Biochem/physiol Actions

IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.