Anti-CD3, low endotoxin antibody, Mouse monoclonal

Molecular Weight: 0
Update Date: 2026-01-13 11:19:52

What is Anti-CD3, low endotoxin antibody, Mouse monoclonal?

The Uses of Anti-CD3, low endotoxin antibody, Mouse monoclonal

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

General Description

The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.

Biochem/physiol Actions

T-cell receptor- CD3 (cluster of differentiation 3) complex including CD3ε, CD3γ and CD3δ play a vital role in inducing early metabolic events that lead to T cell activation. Mutation in CD3ε has been observed in T-B+ NK+ severe combined immunodeficiency (SCID) patients.

Properties of Anti-CD3, low endotoxin antibody, Mouse monoclonal

storage temp.	2-8°C
form	buffered aqueous solution

Safety information for Anti-CD3, low endotoxin antibody, Mouse monoclonal

Computed Descriptors for Anti-CD3, low endotoxin antibody, Mouse monoclonal

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