ANGIOTENSINOGEN
Synonym(s):Angiotensinogen 1-14;Angiotensinogen from hog plasma;Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-leu-Val-Tyr-Ser;Hypertensinogen;Renin substrate
- CAS NO.：64315-16-8
- Empirical Formula: C85H123N21O20
- Molecular Weight: 1759.01
- MDL number: MFCD00133798
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is ANGIOTENSINOGEN?
Purification Methods
This rennin substrate is purified 390-fold from the serum by chromatography on Blue Sepharose, phenyl sepharose, hydroxyapatite and finally by affinity chromatography on 5-hydroxytryptamine (5-HT) sepharose to which it specifically binds to the 5-HT. It is applied to the latter column in 50mM sodium phosphate at pH 7 and after washing, it is eluted by increasing the ionic strength with 100mM sodium phosphate buffer containing 250mM NaCl. The multiple forms are separated by SDSPAGE and have pI 4.40-4.82. [Campbell et al. Biochem J 243 121 1987.]
Properties of ANGIOTENSINOGEN
| storage temp. | −20°C |
| solubility | H2O: 0.3 mg/mL, clear, colorless |
| form | lyophilized powder |
Safety information for ANGIOTENSINOGEN
Computed Descriptors for ANGIOTENSINOGEN
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