Aminoguanidine hydrochloride
- CAS NO.：1937-19-5
- Empirical Formula: CH7ClN4
- Molecular Weight: 110.54608
- MDL number: MFCD00039074
- EINECS: 217-707-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
What is Aminoguanidine hydrochloride?
Description
Aminoguanidine is equipotent to L-
Chemical properties
white to off-white crystals
The Uses of Aminoguanidine hydrochloride
Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.
The Uses of Aminoguanidine hydrochloride
antitussive
The Uses of Aminoguanidine hydrochloride
a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin
What are the applications of Application
Aminoguanidine hydrochloride is an irreversible and selective inhibitor of NOS2
General Description
Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Inhibits both constitutive and inducible nitric oxide synthetase.
Properties of Aminoguanidine hydrochloride
| Melting point: | 162-166 °C(lit.) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Completely soluble in water |
| form | Crystals |
| color | White to off-white |
| Water Solubility | 506.7g/L at 20℃ |
| Merck | 13,440 |
| BRN | 3909606 |
| CAS DataBase Reference | 1937-19-5(CAS DataBase Reference) |
| EPA Substance Registry System | Hydrazinecarboximidamide, monohydrochloride (1937-19-5) |
Safety information for Aminoguanidine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for Aminoguanidine hydrochloride
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