Ambazone
- CAS NO.：539-21-9
- Empirical Formula: C8H11N7S
- Molecular Weight: 237.28
- EINECS: 208-713-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is Ambazone?
Originator
Ambazone,Generic
The Uses of Ambazone
Ambazone is a benzoquidine diimine derivative useful as animal growth substance.
What are the applications of Application
Ambazone is Ambazone is a benzoquidine diimine derivative which has shown to have antiseptic and anti-tumor properties.
Definition
ChEBI: Ambazone is a hydrazone.
Manufacturing Process
To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).
Therapeutic Function
Antiseptic
Properties of Ambazone
| Melting point: | 195°C (rough estimate) |
| Boiling point: | 160°C (rough estimate) |
| Density | 1.2732 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Red to Very Dark Brown |
| Stability: | Very Hygroscopic |
| EPA Substance Registry System | Hydrazinecarbothioamide, 2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]- (539-21-9) |
Safety information for Ambazone
Computed Descriptors for Ambazone
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