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HomeProduct name listAmbazone

Ambazone

Ambazone Structural

What is Ambazone?

Originator

Ambazone,Generic

The Uses of Ambazone

Ambazone is a benzoquidine diimine derivative useful as animal growth substance.

What are the applications of Application

Ambazone is Ambazone is a benzoquidine diimine derivative which has shown to have antiseptic and anti-tumor properties.

Definition

ChEBI: Ambazone is a hydrazone.

Manufacturing Process

To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).

Therapeutic Function

Antiseptic

Properties of Ambazone

Melting point: 195°C (rough estimate)
Boiling point: 160°C (rough estimate)
Density  1.2732 (rough estimate)
refractive index  1.5500 (estimate)
storage temp.  Hygroscopic, Refrigerator, under inert atmosphere
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  Red to Very Dark Brown
Stability: Very Hygroscopic
EPA Substance Registry System Hydrazinecarbothioamide, 2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]- (539-21-9)

Safety information for Ambazone

Computed Descriptors for Ambazone

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