Aluminium glycinate
- CAS NO.:13682-92-3
- Empirical Formula: C2H3AlNO4
- Molecular Weight: 132.03
- MDL number: MFCD00053645
- EINECS: 237-193-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is Aluminium glycinate?
Chemical properties
White or slightly yellow powder. Tasteless. Slightly sweet powder, soluble in water and organic solvents, insoluble in inorganic acid and alkali solutions.
The Uses of Aluminium glycinate
Aluminum Glycinate is an antacid which is used in the treatment of peptic ulceration. It is used in the development of a transdermal hydrogel patch for ferulic acid to treat skin damage induced by UV radiation.
Indications
Aluminum glycinate is a stomach acid neutralizer. It can neutralize gastric acid, reduce gastric acidity, reduce pepsin activity, improve upper abdominal pain and clinical symptoms caused by increased gastric acid, and has astringent and hemostasis effects.?
Pharmaceutical Applications
Aluminium glycinate [Al(NH2CH2COO)(OH)2] is used in anti-acid formulations. For example, Gastralgine; contains, amongst other ingredients, dihydroxy aluminium glycinate [Al(NH2CH2COO)(OH)2], Al(OH)3, magnesium trisilicate and simethicone. It is known to have additionally protective effects from ulcers.
Side Effects
Occasionally mild anorexia, nausea, vomiting, constipation, recovery after drug withdrawal. Large doses can cause intestinal obstruction.
Physiological effects
Aluminium glycinate works by neutralizing stomach acid, which helps to relieve symptoms such as burning in the chest or throat area, a bitter taste in the mouth, a persistent dry cough, pain when lying down, and regurgitation.
Properties of Aluminium glycinate
| Melting point: | >295°C (dec.) |
| storage temp. | Refrigerator |
| solubility | Aqueous Acid (Heated) |
| form | Solid |
| color | White to Off-White |
| Merck | 14,3183 |
| InChI | InChI=1S/C2H4NO2.Al.2O/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);;;/q-1;+4;2*-1/p-1 |
| CAS DataBase Reference | 13682-92-3(CAS DataBase Reference) |
| EPA Substance Registry System | Aluminum, (glycinato-.kappa.N,.kappa.O)dihydroxy-, (T-4)- (13682-92-3) |
Safety information for Aluminium glycinate
Computed Descriptors for Aluminium glycinate
| InChIKey | MHTPGNSJEDJMQW-UHFFFAOYSA-M |
| SMILES | [O-][Al+3]1(NCC(=O)[O-]1)[O-] |
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