Acid-PEG1-t-butyl ester
- CAS NO.：2086689-08-7
- Empirical Formula: C10H18O5
- Molecular Weight: 218.25
- MDL number: MFCD30723273
- Update Date: 2026-01-05 11:31:08
What is Acid-PEG1-t-butyl ester?
Description
Acid-PEG1-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Properties of Acid-PEG1-t-butyl ester
| Boiling point: | 341.9±22.0 °C(Predicted) |
| Density | 1.101±0.06 g/cm3(Predicted) |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 4.27±0.10(Predicted) |
Safety information for Acid-PEG1-t-butyl ester
Computed Descriptors for Acid-PEG1-t-butyl ester
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