(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
Synonym(s):(2-Oxopropylidene)triphenylphosphorane;Acetylmethylene-triphenylphosphorane;Methyl (triphenylphosphoranylidene)methyl ketone;NSC 407394
- CAS NO.：1439-36-7
- Empirical Formula: C21H19OP
- Molecular Weight: 318.35
- MDL number: MFCD00008774
- EINECS: 215-878-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:48:08
What is (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE?
Chemical properties
white to light beige crystalline powder
The Uses of (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.
Properties of (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
| Melting point: | 203-205 °C (lit.) |
| Boiling point: | 478.5±28.0 °C(Predicted) |
| Density | 1.14 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in chloroform. Slightly soluble in methanol. |
| form | Powder |
| color | White to off-white |
| Sensitive | Air Sensitive |
| BRN | 750077 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 1439-36-7(CAS DataBase Reference) |
Safety information for (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one](https://img.chemicalbook.in/CAS/GIF/851067-56-6.gif)
You may like
-
(Acetylmethylene)triphenylphosphorane CAS 1439-36-7View Details
1439-36-7 -
1-(Triphenylphosphoranylidene)-2-propanone CAS 1439-36-7View Details
1439-36-7 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.