Acetylene-PEG4-biotin conjugate
Synonym(s):Acetylene-PEG4-biotin conjugate
- CAS NO.：1458576-00-5
- Empirical Formula: C21H35N3O6S
- Molecular Weight: 457.58
- MDL number: MFCD22380755
- Update Date: 2025-12-23 13:58:55
What is Acetylene-PEG4-biotin conjugate?
Description
Biotin-PEG4-alkyne is click chemistry biotinylation reagent. The alkyne group is reactive with azide moiety via Click Chemistry reaction to form a stable triazole linkage. PEG arm increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
The Uses of Acetylene-PEG4-biotin conjugate
An acetylene-biotin conjugate with PEG spacer
Properties of Acetylene-PEG4-biotin conjugate
| Melting point: | 55-64 °C |
| Boiling point: | 707.1±60.0 °C(Predicted) |
| Density | 1.158±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 13.90±0.40(Predicted) |
| form | Solid |
| color | White to light yellow |
Safety information for Acetylene-PEG4-biotin conjugate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for Acetylene-PEG4-biotin conjugate
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