ACETOPHENAZINE MALEATE (200 MG)
Synonym(s):Acetophenazine dimaleate salt
- CAS NO.：5714-00-1
- Empirical Formula: C53H64N6O11S2
- Molecular Weight: 1025.23886
- MDL number: MFCD26142854
- EINECS: 227-202-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-13 13:05:00
What is ACETOPHENAZINE MALEATE (200 MG)?
Originator
Tindal ,Schering ,US ,1961
The Uses of ACETOPHENAZINE MALEATE (200 MG)
Antipsychotic.
Definition
ChEBI: A maleate salt obtained by combining acetophenazine with two molar equivalents of maleic acid.
Manufacturing Process
The requisite intermediate, 10-(3-chloropropyl)-2-acetylphenothiazineis
prepared as follows: To a suspension of sodium amide (from 3 grams of
sodium) in 300 ml of liquid ammonia is added 30 grams of 2-
acetylphenothiazine. After stirring for one hour, there is added 19 grams of 1-
bromo-3-chloropropane. The ammonia is allowed to evaporate and the residue
is diluted with 200 ml of water. The mixture is extracted with ether and the
ether solution is dried over anhydrous sodium sulfate, filtered and
concentrated.
The residue consists of crude 10-(3-chloropropy1)-2-acetylphenothiazine as a
viscous oil and is used in the next step without further purification. The crude
base obtained from the reaction of 10-(3-chloropropyl)-2-acetylphenothiazine
with 1-(2-hydroxyethyl)piperazine is purified by conversion to its dimaleate
salt, MP 167-168.5°C from ethanol.
brand name
Tindal (Schering).
Therapeutic Function
Tranquilizer
Safety Profile
Poison by ingestion, intraperitoneal,and intravenous routes. Severe eye irritant.
Properties of ACETOPHENAZINE MALEATE (200 MG)
| Melting point: | 167-168.5° |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| form | Solid |
| color | Yellow to Orange |
| Stability: | Hygroscopic |
Safety information for ACETOPHENAZINE MALEATE (200 MG)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ACETOPHENAZINE MALEATE (200 MG)
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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