ABT 894
- CAS NO.：799279-80-4
- Empirical Formula: C10H11Cl2N3
- Molecular Weight: 244.12
- MDL number: MFCD19443714
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-28 15:00:41
What is ABT 894?
Biological Activity
Sofiniclin (ABT 894) is an agonist of nAChR as a potential non-stimulatory study in attention deficit disorder.
in vitro
ABT 894 is more potent than ABT-089 at both receptor subtypes, with K i values of 1.9 nM for 125 I-α-conotoxinMII binding and of 1.3 nM for 125 I-epibatidine binding.
in vivo
ABT 894 (0.001 to 0.10 mg/kg, po) produces significant reductions in LIDs compared to vehicle monkey. It does not decrease LIDs in monkeys with severe nigrostriatal damage.
< p>Properties of ABT 894
| Boiling point: | 417.4±45.0 °C(Predicted) |
| Density | 1.406±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 10.31±0.20(Predicted) |
| color | Off-white to brown |
Safety information for ABT 894
Computed Descriptors for ABT 894
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