Delafloxacin meglumine
- CAS NO.：352458-37-8
- Empirical Formula: C18H12ClF3N4O4.C7H17NO5
- Molecular Weight: 635.97
- MDL number: MFCD26142921
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is Delafloxacin meglumine?
Description
Delafloxacin meglumine (Baxdela, WQ-3034, ABT-492, RX-3341; Melinta Therapeutics) was approved by the U.S. Food and Drug Administration (FDA) in June 2017 for the treatment of acute bacterial skin and skin structure infections on the basis of data from two phase III trials.
The Uses of Delafloxacin meglumine
Delafloxacin is a broad-spectrum anionic fluoroquinolone and its distinct chemical structure increases its potency in acidic environments. It is known to inhibit DNA replication and repair by targeting DNA gyrase and topoisomerase IV. Delafloxacin is administered via both oral and parenteral routes. It has potent activity against methicillin-resistant Staphylococcus aureus and Streptococci, and is also effective against Enterobacteriaceae and Pseudomonas aeruginosa.
Biological Activity
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine is a broad spectrum fluoroquinolone antibiotic. Delafloxacin has a wide range of activity against drug-resistant Staphylococcus aureus, Streptococcus pneumoniae and Klebsiella pneumoniae.
Properties of Delafloxacin meglumine
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in DMSO |
| form | Powder |
| color | Off-white to yellow |
Safety information for Delafloxacin meglumine
Computed Descriptors for Delafloxacin meglumine
Delafloxacin meglumine manufacturer
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group)
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