AAL Toxin TA1
- CAS NO.:79367-52-5
- Empirical Formula: C25H47NO10
- Molecular Weight: 521.64
What is AAL Toxin TA1?
Enzyme inhibitor
These sphingoid-like alkaloids (AAL Toxin TA1; FW = 521.64 g/mL; CAS 79367-52-5; AAL Toxin TA2; FW = 521.65 g/mol; CAS 79367-51-4) from the ascomycete fungus Alternaria alternata inhibit ceramide synthase, an early biochemical event in the animal diseases associated with consumption of Fusarium moniliforme-contaminated corn. Because free sphingoid bases are precursors to plant “ceramides,” their accumulation suggests that the primary biochemical lesion is inhibition of de novo ceramide synthesis and re-acylation of free sphingoid bases. Target(s): ceramide synthase, or sphingosine N-acyltransferase.
Safety information for AAL Toxin TA1
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