8-Hydroxyquinoline-5-sulfonic acid
- CAS NO.：84-88-8
- Empirical Formula: C9H7NO4S
- Molecular Weight: 225.22
- MDL number: MFCD00006795
- EINECS: 201-570-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-13 19:59:05
What is 8-Hydroxyquinoline-5-sulfonic acid?
Chemical properties
Yellow fine crystalline powder
The Uses of 8-Hydroxyquinoline-5-sulfonic acid
8-Hydroxy-5-quinolinesulfonic acid is used in the synthesis of fat mass and obesity associated proteins. Also used in the synthesis of anti-schitosomal compounds.
Purification Methods
Crystallise the acid from water (as the 1.5 hydrate, m 316-317o) or dilute HCl (ca 2% by weight). [Beilstein 22 I 620, 22 II 313, 22 III/IV 3493.]
Properties of 8-Hydroxyquinoline-5-sulfonic acid
| Melting point: | 311-313°C |
| Density | 1.4899 (rough estimate) |
| refractive index | 1.5364 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| pka | pK1:4.092(＋1);pK2:8.776(0) (25°C) |
| form | crystalline |
| color | yellow to green |
| Merck | 4844 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 84-88-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Quinolinesulfonic acid, 8-hydroxy-(84-88-8) |
| EPA Substance Registry System | 5-Quinolinesulfonic acid, 8-hydroxy- (84-88-8) |
Safety information for 8-Hydroxyquinoline-5-sulfonic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 8-Hydroxyquinoline-5-sulfonic acid
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