7-Fluoro-4-quinazolone
- CAS NO.：16499-57-3
- Empirical Formula: C8H5FN2O
- Molecular Weight: 164.14
- MDL number: MFCD07689443
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-07 08:31:03
What is 7-Fluoro-4-quinazolone?
The Uses of 7-Fluoro-4-quinazolone
7-Fluoro-4-quinazolone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity.It is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).
The Uses of 7-Fluoro-4-quinazolone
7-Fluoro-4(3H)-quinazolinone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity. 7-Fluoro-4(3H)-quinazolinone is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).
Properties of 7-Fluoro-4-quinazolone
| Melting point: | 246.0 to 250.0 °C |
| Boiling point: | 293.3±42.0 °C(Predicted) |
| Density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 0.51±0.20(Predicted) |
| color | White to Gray to Red |
| CAS DataBase Reference | 16499-57-3(CAS DataBase Reference) |
Safety information for 7-Fluoro-4-quinazolone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 7-Fluoro-4-quinazolone
| InChIKey | KCORZHJVTZIZFD-UHFFFAOYSA-N |
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